产品名：重组人VEGF 165（VEGF-A）

产品号：LT0221 产品信息： VEGF是血管内皮细胞特异性肝结合生长因子，包括VEGF121、VEGF145、VEGF165、VEGF189和VEGF206。VEGF可作用于血管内皮细胞，具有促进内皮细胞的增殖、迁移及成管等功能。在大多数肿瘤中VEGF通过与VEGFR相互作用上调新生血管的产生，其中VEGF165的影响作用最为重要。

别名: Vascular Endothelial Growth Factor, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF-A

英文描述: VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

表达宿主来源: E.coli

氨基酸序列: APMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR

保存条件： 4℃保存6个月，-20℃保存一年或-80℃长期保存。

纯度&内毒素： Greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin Level<0.5EU//μg